SCHEMBL1779820

SCHEMBL1779820

O=C(On1nnc2ccccc21)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 5/20 0.74
HDAC4 P56524 5/20 0.74
HDAC1 Q13547 5/20 0.74
HDAC7 Q8WUI4 5/20 0.74
HDAC2 Q92769 5/20 0.74
HDAC10 Q969S8 5/20 0.74
HDAC11 Q96DB2 5/20 0.74
HDAC8 Q9BY41 5/20 0.74
HDAC6 Q9UBN7 5/20 0.74
HDAC9 Q9UKV0 5/20 0.74
HDAC5 Q9UQL6 5/20 0.74
SIRT2 Q8IXJ6 4/20 0.70
MGAM O43451 2/20 0.55
AMY1A P0DUB6 2/20 0.55
GAA P10253 2/20 0.55
SI P14410 2/20 0.55
MGAM2 Q2M2H8 2/20 0.55
F2 P00734 1/20 0.55
HPGD P15428 1/20 0.55
SLC9A1 P19634 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12430571 0.92 HDAC3 (0.73) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL7413562 0.91 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL69679 0.91 HDAC3 (0.69) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL69680 0.89 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL4868536 0.88 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2298574 0.88 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL6539230 0.88 HDAC3 (0.80) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL4953766 0.88 HDAC3 (0.80) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL7317724 0.86 HDAC3 (1.00) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8827885 0.86 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582737-B2 Orthogonally protected disaccharide building blocks for synthesis of heparin oligosaccharides ACADEMIA SINICA (TW) 2009-09-01 US claimed
CN-101289475-A Process for selectively synthesizing sucrose-6-ester CHANGZHOU NIUTANG CHEMICAL PLA (CN) 2008-10-22 CN claimed
US-20250007001-A1 LITHIUM SECONDARY BATTERY TERAWATT TECHNOLOGY K.K. (JP) 2025-01-02 US disclosed
US-20240250306-A1 LITHIUM SECONDARY BATTERY TERAWATT TECHNOLOGY K.K. (JP) 2024-07-25 US disclosed
WO-2023170799-A1 LITHIUM SECONDARY BATTERY TeraWatt Technology株式会社 2023-09-14 WO disclosed
US-20230261203-A1 LITHIUM SECONDARY BATTERY TERAWATT TECHNOLOGY K.K. (JP) 2023-08-17 US disclosed
US-20230261203-A1 LITHIUM SECONDARY BATTERY TERAWATT TECHNOLOGY K.K. (JP) 2023-08-17 US disclosed
US-20230261203-A1 LITHIUM SECONDARY BATTERY TERAWATT TECHNOLOGY K.K. (JP) 2023-08-17 US disclosed
WO-2023053295-A1 LITHIUM SECONDARY BATTERY TeraWatt Technology株式会社 2023-04-06 WO disclosed
WO-2022085046-A1 LITHIUM SECONDARY BATTERY TeraWatt Technology株式会社 2022-04-28 WO disclosed
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed
EP-1322673-A1 POLYSACCHARIDES WITH ANTITHROMBOTIC ACTIVITY COMPRISING AT LEAST A COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE Sanofi-Aventis (FR) 2003-07-02 EP disclosed
US-6534481-B1 Antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four sulpho groups, said domain being directly bound at the non-reducing end by a thrombin SANOFI-SYNTHELABO (FR) 2003-03-18 US disclosed
EP-0912613-B1 SYNTHETIC POLYSACCHARIDES, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SANOFI SYNTHELABO (FR) 2002-09-25 EP disclosed
WO-2002024754-A1 POLYSACCHARIDES WITH ANTITHROMBOTIC ACTIVITY COMPRISING AT LEAST A COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE SANOFI-SYNTHELABO (FR) 2002-03-28 WO disclosed
EP-1049721-B1 SYNTHETIC POLYSACCHARIDES, THEIR METHOD OF PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SANOFI SYNTHELABO (FR) 2001-11-21 EP disclosed
CN-1228785-A Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same SANOFI SA (FR) 1999-09-15 CN disclosed
US-4388233-A PROTEOLYTIC ENZYMES, FLUORIMETRIC ANALYSIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1983-06-14 US disclosed
US-4242507-A Sulfonic acid esters FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 US disclosed
US-4075220-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 HDAC3 4081/4885HDAC4 4114/4885HDAC1 3911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.