Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16608426 | 0.87 | FDPS (0.41) | FDPSTBXAS1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL26793511 | 0.82 | FDPS (0.46) | FDPSTBXAS1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8388811 | 0.82 | FDPS (0.46) | FDPSTBXAS1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL26838403 | 0.82 | FDPS (0.46) | FDPSTBXAS1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL26803149 | 0.82 | FDPS (0.46) | FDPSTBXAS1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL25290547 | 0.80 | TBXAS1 (0.50) | TBXAS1CYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL7667526 | 0.80 | FDPS (0.49) | FDPSCYP19A1MEN1KMT2A | |
| SCHEMBL4962049 | 0.80 | FDPS (0.44) | FDPSTBXAS1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8388764 | 0.79 | TBXAS1 (0.46) | FDPSTBXAS1CYP19A1ALDH1A1MAPK1 | |
| SCHEMBL25293366 | 0.77 | TBXAS1 (0.57) | TBXAS1CYP19A1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790161-A | Pyrazolopyridine derivatives having GLP-1 receptor agonist action | 中外制药株式会社 | 2019-05-21 | — | — | CN | disclosed |
| US-5015641-A | Dipeptide for vision defects | ANDREWS DAVID R (US) | 1991-05-14 | — | — | US | disclosed |
| US-4885293-A | CARBOXYALKYL DIPEPTIDES | SCHERING CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| US-4826816-A | Antihypertensive compounds | SCHERING CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |