Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417953 | 0.94 | MCHR1 (0.52) | SLC6A2SLC6A4SLC6A3MCHR1FAAH | |
| Hydrochloric Acid SCHEMBL7419435 | 0.93 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3MCHR1FAAH | |
| SCHEMBL7414785 | 0.93 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3MCHR1FAAH | |
| SCHEMBL7412318 | 0.90 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3MCHR1FAAH | |
| SCHEMBL7409350 | 0.90 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3MCHR1FAAH | |
| SCHEMBL7458788 | 0.89 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3MCHR1FAAH | |
| SCHEMBL7415717 | 0.87 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3MCHR1FAAH | |
| SCHEMBL7467533 | 0.85 | MC4R (0.49) | SLC6A2SLC6A4SLC6A3MCHR1FAAH | |
| SCHEMBL7413468 | 0.82 | FAAH (0.53) | SLC6A2SLC6A4SLC6A3MCHR1FAAH | |
| SCHEMBL7410337 | 0.82 | ACHE (0.55) | SLC6A2SLC6A4SLC6A3MCHR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |