Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 1.00 |
| ▸ | FBP1 | P09467 | 15/20 | 0.55 |
| ▸ | VCP | P55072 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040118 | 1.00 | HSP90AA1 (1.00) | HSP90AA1FBP1VCPMEN1ALDH1A1 | |
| SCHEMBL3861356 | 0.87 | HSP90AA1 (0.77) | HSP90AA1FBP1VCPALDH1A1KMT2A | |
| SCHEMBL3861363 | 0.87 | HSP90AA1 (0.77) | HSP90AA1FBP1VCPALDH1A1KMT2A | |
| SCHEMBL34462896 | 0.83 | HSP90AA1 (0.70) | HSP90AA1FBP1VCPALDH1A1TDP1 | |
| SCHEMBL11805779 | 0.82 | HSP90AA1 (0.69) | HSP90AA1FBP1VCPALDH1A1TDP1 | |
| SCHEMBL10513164 | 0.79 | HSP90AA1 (0.65) | HSP90AA1FBP1VCPMEN1ALDH1A1 | |
| SCHEMBL10513157 | 0.79 | HSP90AA1 (0.65) | HSP90AA1FBP1VCPMEN1ALDH1A1 | |
| SCHEMBL104148 | 0.78 | HSP90AA1 (0.63) | HSP90AA1FBP1VCPMEN1ALDH1A1 | |
| SCHEMBL29925427 | 0.78 | HSP90AA1 (0.63) | HSP90AA1FBP1VCPMEN1ALDH1A1 | |
| SCHEMBL104147 | 0.78 | HSP90AA1 (0.63) | HSP90AA1FBP1VCPMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12006294-B2 | Therapeutic compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-06-11 | — | — | US | disclosed |
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2019-10-31 | — | — | US | disclosed |
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2019-10-31 | — | — | US | disclosed |
| WO-1988003147-A1 | SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | disclosed |
| US-4126685-A | 6-Aryl-pyrrolo[1,2,9]imidazole derivatives which possess anti-hypertensive activity | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | OPRL1, INA, OGFR | HSP90AA1 3237/4885FBP1 3534/4885VCP 4157/4885 |
| US-12006294-B2 | Therapeutic compounds | OPRL1, INA, OGFR | HSP90AA1 3237/4885FBP1 3534/4885VCP 4157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.