SCHEMBL7414407

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@H]([C]=O)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	11/20	0.54

▸	NPY1R	P25929	6/20	0.54

▸	NPY2R	P49146	4/20	0.54

▸	NPY5R	Q15761	4/20	0.54

▸	KISS1R	Q969F8	2/20	0.51

▸	BACE1	P56817	3/20	0.50

▸	KEAP1	Q14145	1/20	0.49

▸	MDM4	O15151	1/20	0.48

▸	MDM2	Q00987	1/20	0.48

▸	VIPR2	P41587	2/20	0.47

▸	VIPR1	P32241	1/20	0.47

▸	BACE2	Q9Y5Z0	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7420426	0.96	NPY4R (0.48)	NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL2183401	0.88	NPY4R (0.63)	NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL7414767	0.86	F2 (0.49)	NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL9843134	0.86	VIPR2 (0.56)	NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL9843124	0.86	VIPR2 (0.56)	NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL7415877	0.85	F2 (0.47)	NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL30185757	0.85	NPY4R (0.57)	NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL30512539	0.85	VIPR2 (0.58)	NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL31415959	0.84	NPY4R (0.56)	NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL31005900	0.84	BACE1 (0.59)	NPY4RBACE1MDM4MDM2VIPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1990014362-A1	ATRIAL PEPTIDE DERIVATIVES	ABBOTT LABORATORIES (US)	1990-11-29	—	—	WO	disclosed