Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | NPY4R | P50391 | 10/20 | 0.47 |
| ▸ | NPY1R | P25929 | 6/20 | 0.47 |
| ▸ | NPY2R | P49146 | 4/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459011 | 0.97 | BACE1 (0.47) | F2NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7419273 | 0.91 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7469871 | 0.90 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RBACE1 | |
| SCHEMBL7420426 | 0.89 | NPY4R (0.48) | F2NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7417585 | 0.88 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL7414767 | 0.87 | F2 (0.49) | F2NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7469236 | 0.86 | IL23R (0.48) | F2NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7414407 | 0.85 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL31657703 | 0.85 | KISS1R (0.53) | F2NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7467426 | 0.84 | PTH1R (0.48) | KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040102-A4 | ARYLTHIAZOLIDINEDIONE DERIVATIVES | MERCK & CO INC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1194146-A4 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | MERCK & CO INC (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-1194146-A1 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | Merck & Co., Inc. (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078312-A1 | ARYLTHIAZOLIDINEDIONE AND ARYLOXAZOLIDINEDIONE DERIVATIVES | MERCK & CO., INC. (US) | 2000-12-28 | — | — | WO | disclosed |
| EP-1040102-A1 | ARYLTHIAZOLIDINEDIONE DERIVATIVES | Merck & Co., Inc. (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032465-A1 | ARYLTHIAZOLIDINEDIONE DERIVATIVES | MERCK & CO., INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| EP-0431113-A4 | ATRIAL PEPTIDE DERIVATIVES | — | 1992-01-22 | — | — | EP | disclosed |
| EP-0431113-A1 | ATRIAL PEPTIDE DERIVATIVES | ABBOTT LABORATORIES (US) | 1991-06-12 | — | — | EP | disclosed |
| WO-1990014362-A1 | ATRIAL PEPTIDE DERIVATIVES | ABBOTT LABORATORIES (US) | 1990-11-29 | — | — | WO | disclosed |