Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 9/20 | 0.44 |
| ▸ | NPY1R | P25929 | 7/20 | 0.44 |
| ▸ | NPY2R | P49146 | 5/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.44 |
| ▸ | VIPR1 | P32241 | 1/20 | 0.42 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420426 | 0.89 | NPY4R (0.48) | F2KISS1RBACE1NPY4RNPY1R | |
| SCHEMBL7415877 | 0.87 | F2 (0.47) | F2KISS1RBACE1NPY4RNPY1R | |
| SCHEMBL30938822 | 0.86 | F2 (0.50) | F2KISS1RBACE1NPY4RNPY1R | |
| SCHEMBL7414407 | 0.86 | NPY4R (0.54) | KISS1RBACE1NPY4RNPY1RNPY2R | |
| SCHEMBL7461891 | 0.86 | ENPEP (0.46) | — | |
| SCHEMBL7469236 | 0.85 | IL23R (0.48) | F2NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7459011 | 0.85 | BACE1 (0.47) | F2KISS1RBACE1NPY4RNPY1R | |
| SCHEMBL31657703 | 0.84 | KISS1R (0.53) | F2KISS1RBACE1NPY4RNPY1R | |
| SCHEMBL7467426 | 0.83 | PTH1R (0.48) | KISS1R | |
| SCHEMBL30543294 | 0.83 | BACE1 (0.53) | F2KISS1RBACE1NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431113-A4 | ATRIAL PEPTIDE DERIVATIVES | — | 1992-01-22 | — | — | EP | disclosed |
| EP-0431113-A1 | ATRIAL PEPTIDE DERIVATIVES | ABBOTT LABORATORIES (US) | 1991-06-12 | — | — | EP | disclosed |
| WO-1990014362-A1 | ATRIAL PEPTIDE DERIVATIVES | ABBOTT LABORATORIES (US) | 1990-11-29 | — | — | WO | disclosed |