Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | KLK8 | O60259 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 2/20 | 0.43 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414689 | 1.00 | FOLH1 (0.47) | FOLH1SIRT5CTSLCTSSSIRT2 | |
| SCHEMBL8995576 | 0.88 | CTSS (0.53) | FOLH1SIRT5CTSLCTSSSIRT2 | |
| SCHEMBL8995578 | 0.88 | CTSS (0.53) | FOLH1SIRT5CTSLCTSSSIRT2 | |
| SCHEMBL7417445 | 0.86 | F2 (0.54) | FOLH1SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL7417435 | 0.86 | F2 (0.54) | FOLH1SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL7417654 | 0.85 | FOLH1 (0.53) | FOLH1SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL7415256 | 0.85 | FOLH1 (0.53) | FOLH1SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL7414657 | 0.85 | FOLH1 (0.53) | FOLH1SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL14132310 | 0.79 | F10 (0.52) | FOLH1SIRT5CTSLCTSSSIRT2 | |
| SCHEMBL8995573 | 0.78 | CTSS (0.50) | CTSLCTSSSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1993012074-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |