Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.50 |
| ▸ | CTSL | P07711 | 6/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409808 | 1.00 | CTSS (0.50) | CTSSCTSLCTSBMEN1ALDH1A1 | |
| SCHEMBL8995546 | 0.89 | CTSS (0.53) | CTSSCTSLCTSBMEN1ALDH1A1 | |
| SCHEMBL8995544 | 0.89 | CTSS (0.53) | CTSSCTSLCTSBMEN1ALDH1A1 | |
| SCHEMBL8995578 | 0.89 | CTSS (0.53) | CTSSCTSLCTSBMEN1ALDH1A1 | |
| SCHEMBL8995576 | 0.89 | CTSS (0.53) | CTSSCTSLCTSBMEN1ALDH1A1 | |
| SCHEMBL7418533 | 0.89 | CTSS (0.52) | CTSSCTSLCTSBMEN1ALDH1A1 | |
| SCHEMBL8995549 | 0.89 | CTSS (0.52) | CTSSCTSLCTSBMEN1ALDH1A1 | |
| SCHEMBL7423262 | 0.89 | CTSS (0.52) | CTSSCTSLCTSBMEN1ALDH1A1 | |
| SCHEMBL23451331 | 0.83 | MEN1 (0.62) | MEN1ALDH1A1HPGDKMT2ABCHE | |
| SCHEMBL23451332 | 0.83 | MEN1 (0.62) | MEN1ALDH1A1HPGDKMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |