Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 17/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 8/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415833 | 0.91 | ITGA4 (0.55) | ITGA4ITGB1ITGB7PPARGPPARA | |
| SCHEMBL7413502 | 0.90 | ECE1 (0.44) | ITGA4ITGB1ITGB7PPARA | |
| SCHEMBL7417516 | 0.88 | ITGA4 (0.59) | ITGA4ITGB1ITGB7PPARGPPARA | |
| SCHEMBL7417523 | 0.88 | ITGA4 (0.59) | ITGA4ITGB1ITGB7PPARGPPARA | |
| SCHEMBL8932450 | 0.87 | MME (0.47) | PPARGPPARA | |
| SCHEMBL7415763 | 0.84 | MME (0.49) | — | |
| SCHEMBL7407908 | 0.83 | KMT2A (0.47) | — | |
| SCHEMBL7411383 | 0.80 | ITGA4 (0.43) | ITGA4ITGB1ITGB7PPARA | |
| SCHEMBL7418112 | 0.80 | PDCD1 (0.43) | PPARGPPARA | |
| SCHEMBL8923001 | 0.80 | PPARG (0.41) | ITGA4ITGB1ITGB7PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996026729-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES AS ECE INHIBITORS | CIBA-GEIGY AG (CH) | 1996-09-06 | — | — | WO | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | disclosed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |