Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.47 |
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415763 | 0.90 | MME (0.49) | MMEACEKMT2A | |
| SCHEMBL7411238 | 0.89 | PPARG (0.48) | MMEACEPPARGPPARAECE1 | |
| SCHEMBL7407908 | 0.89 | KMT2A (0.47) | MMEACEECE1MEN1KMT2A | |
| SCHEMBL7413345 | 0.88 | MME (0.46) | MMEACEPPARGPPARAECE1 | |
| SCHEMBL7407175 | 0.88 | MME (0.48) | MMEACEPPARGPPARACPA1 | |
| SCHEMBL7410891 | 0.88 | FPR2 (0.46) | MMEACEPPARGPPARAMEN1 | |
| SCHEMBL7414734 | 0.87 | ITGA4 (0.54) | PPARGPPARA | |
| SCHEMBL7316584 | 0.84 | MMEL1 (0.57) | MMEACE | |
| SCHEMBL7310423 | 0.84 | MMEL1 (0.57) | MMEACE | |
| SCHEMBL7411127 | 0.84 | MME (0.62) | MMEACEECE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026729-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES AS ECE INHIBITORS | CIBA-GEIGY AG (CH) | 1996-09-06 | — | — | WO | disclosed |