Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409790 | 0.84 | GAA (0.54) | GAAHTTHPGDALDH1A1KDM4E | |
| SCHEMBL167764 | 0.80 | POLB (0.51) | GAAHTTHPGDALDH1A1KDM4E | |
| SCHEMBL7407421 | 0.78 | HTT (0.51) | GAAHTTHPGDALDH1A1KDM4E | |
| SCHEMBL27410742 | 0.78 | GAA (0.59) | GAAHTTHPGDALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7418823 | 0.77 | GAA (0.46) | GAAHTTHPGDALDH1A1KDM4E | |
| SCHEMBL7410882 | 0.77 | HTT (0.57) | GAAHTTHPGDALDH1A1KDM4E | |
| SCHEMBL20539831 | 0.75 | HTT (0.46) | GAAHTTHPGDALDH1A1KDM4E | |
| SCHEMBL168791 | 0.75 | GAA (0.46) | GAAHTTHPGDALDH1A1KDM4E | |
| SCHEMBL3655431 | 0.73 | KDM4E (0.49) | GAAHTTHPGDALDH1A1KDM4E | |
| SCHEMBL7419408 | 0.72 | GAA (0.74) | GAAHTTHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |