Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167764 | 0.88 | POLB (0.51) | GAAHTTPOLBHPGDKDM4E | |
| SCHEMBL7407421 | 0.85 | HTT (0.51) | GAAHTTPOLBHPGDKDM4E | |
| SCHEMBL7414737 | 0.84 | GAA (0.50) | GAAHTTPOLBHPGDKDM4E | |
| SCHEMBL7410882 | 0.84 | HTT (0.57) | GAAHTTPOLBHPGDKDM4E | |
| SCHEMBL7419408 | 0.83 | GAA (0.74) | GAAHTTPOLBHPGDKDM4E | |
| SCHEMBL20539831 | 0.83 | HTT (0.46) | GAAHTTPOLBHPGDKDM4E | |
| SCHEMBL168791 | 0.83 | GAA (0.46) | GAAHTTPOLBHPGDKDM4E | |
| SCHEMBL1953848 | 0.80 | GAA (0.58) | GAAHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL7414042 | 0.79 | ABL1 (0.54) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28975019 | 0.77 | TNFSF11 (0.66) | GAAHTTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |