Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340509 | 0.77 | — | — | |
| SCHEMBL408136 | 0.69 | TSHR (0.33) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL9341903 | 0.69 | — | — | |
| SCHEMBL8550233 | 0.67 | CA4 (0.38) | — | |
| SCHEMBL407818 | 0.63 | POLB (0.33) | — | |
| SCHEMBL10960566 | 0.61 | ALDH1A1 (0.30) | TSHRALDH1A1 | |
| Oxalic Acid SCHEMBL10733846 | 0.59 | ALDH1A1 (0.35) | TSHRALDH1A1 | |
| Oxalic Acid SCHEMBL10733835 | 0.59 | ALDH1A1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL3381436 | 0.59 | — | — | |
| SCHEMBL3982859 | 0.59 | TSHR (0.41) | TSHRALDH1A1CYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |