SCHEMBL407818

SCHEMBL407818

CNN(C(=O)C(=O)O)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1644184 0.79 POLB (0.35) POLBCYP3A4CYP2C9
SCHEMBL8195428 0.75
SCHEMBL21585748 0.70 POLB (0.37) POLBCYP2C9
SCHEMBL408136 0.65 TSHR (0.33)
SCHEMBL7414826 0.63 TSHR (0.32)
SCHEMBL11525181 0.62 POLB (0.38) POLBCYP3A4CYP2C9
SCHEMBL16166384 0.62 POLB (0.34) POLBCYP3A4CYP2C9
Oxalic Acid SCHEMBL10733846 0.61 ALDH1A1 (0.35)
Oxalic Acid SCHEMBL10733835 0.61 ALDH1A1 (0.35)
Bicarbonate SCHEMBL10734019 0.58 ALDH1A1 (0.37) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2394986-B1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT AGRO KANESHO CO LTD (JP) 2013-12-04 EP disclosed
US-8541473-B2 3-aminoxalyl-aminobenzamide derivatives and insecticidal and miticidal agents containing same as active ingredient AGRO-KANESHO CO., LTD. (JP) 2013-09-24 US disclosed
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT AGRO-KANESHO CO., LTD. (JP) 2012-01-26 US disclosed
EP-2394986-A1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT Agro-Kanesho Co., Ltd. (JP) 2011-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT HDHD5, CBR3, BAK1 POLB 3622/4885CYP3A4 405/4885CYP2C9 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.