Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | HPN | P05981 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414884 | 1.00 | F2 (0.47) | F2F10PRSS1PLAUHPN | |
| SCHEMBL7423099 | 0.88 | ITGB3 (0.54) | PLAUHPNITGB3ITGA2BST14 | |
| SCHEMBL7423093 | 0.88 | ITGB3 (0.54) | PLAUHPNITGB3ITGA2BST14 | |
| SCHEMBL7417659 | 0.81 | MEN1 (0.56) | F2F10PLAUMEN1ALDH1A1 | |
| SCHEMBL7409898 | 0.81 | MEN1 (0.56) | F2F10PLAUMEN1ALDH1A1 | |
| SCHEMBL7387496 | 0.79 | ITGB3 (0.54) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL7388775 | 0.76 | F2 (0.46) | F2F10PRSS1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7297924 | 0.75 | F2 (0.58) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL7384718 | 0.73 | F2 (0.45) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL7423101 | 0.73 | S1PR2 (0.38) | ITGB3ITGA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | claimed |
| WO-1993012074-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | claimed |
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |