Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414798 | 0.82 | SHMT2 (0.51) | MAPTALDH1A1MEN1GAAPKM | |
| Fumaric Acid SCHEMBL30357950 | 0.78 | MAPT (0.48) | MAPTALDH1A1MEN1GAAPKM | |
| SCHEMBL8894236 | 0.75 | SHMT2 (0.50) | MAPTALDH1A1MEN1GAAPKM | |
| SCHEMBL8894242 | 0.75 | SHMT2 (0.50) | MAPTALDH1A1MEN1GAAPKM | |
| SCHEMBL7435099 | 0.71 | ATM (0.76) | MAPTALDH1A1MEN1KMT2ASLC2A1 | |
| SCHEMBL515430 | 0.70 | SLC2A1 (0.74) | ALDH1A1MEN1KMT2ASLC2A1SMPD1 | |
| Hydrochloric Acid SCHEMBL11808765 | 0.70 | ATM (0.73) | MAPTALDH1A1MEN1KMT2ASLC2A1 | |
| Bromide SCHEMBL11515734 | 0.69 | SLC2A1 (0.72) | ALDH1A1MEN1KMT2ASLC2A1SMPD1 | |
| SCHEMBL13344551 | 0.67 | SLC2A1 (0.87) | MAPTALDH1A1MEN1KMT2ASLC2A1 | |
| SCHEMBL8853801 | 0.66 | HDAC1 (0.51) | MAPTALDH1A1GAATP53HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584292-A | Antihypertensive 1,5-benzothiazepine derivatives and compositions thereof | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1986-04-22 | — | — | US | claimed |