Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | XIAP | P98170 | 3/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132571 | 0.86 | NPY1R (0.59) | SCN9ANPY1RPYGLXIAP | |
| SCHEMBL7416762 | 0.86 | NPY1R (0.59) | SCN9ANPY1RPYGLXIAP | |
| SCHEMBL7416731 | 0.85 | PYGL (0.44) | SCN9ANPY1RPYGLACEXIAP | |
| SCHEMBL4997504 | 0.85 | SCN9A (0.49) | SCN9ANPY1RXIAPPPARA | |
| SCHEMBL4997515 | 0.85 | SCN9A (0.49) | SCN9ANPY1RXIAPPPARA | |
| SCHEMBL7418257 | 0.84 | PYGL (0.52) | SCN9ANPY1RPYGL | |
| SCHEMBL7423984 | 0.84 | SCN9A (0.50) | SCN9ANPY1R | |
| SCHEMBL7421160 | 0.83 | SCN9A (0.48) | SCN9ANPY1RACE | |
| SCHEMBL4985454 | 0.83 | SCN9A (0.56) | SCN9A | |
| SCHEMBL4257988 | 0.83 | CYP3A4 (0.44) | SCN9ANPY1RXIAPPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |