Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 2/20 | 0.32 |
| ▸ | PRKACG | P22612 | 2/20 | 0.32 |
| ▸ | PRKACB | P22694 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411153 | 0.81 | TDP1 (0.34) | MAT2A | |
| SCHEMBL7412394 | 0.81 | SRC (0.43) | SRCHSD17B10GPR35 | |
| Bromide SCHEMBL10733467 | 0.80 | SRC (0.42) | SRCHSD17B10GPR35 | |
| Water SCHEMBL7408556 | 0.80 | SRC (0.42) | SRCHSD17B10GPR35 | |
| Potassium Ion SCHEMBL7409882 | 0.78 | SRC (0.38) | SRCMAT2AHSD17B10GPR35PRKACA | |
| Potassium Ion SCHEMBL7415696 | 0.78 | SRC (0.38) | SRCMAT2AHSD17B10GPR35PRKACA | |
| Ethylamine SCHEMBL7408665 | 0.76 | SRC (0.43) | SRCHSD17B10GPR35 | |
| SCHEMBL10621799 | 0.76 | TNF (0.47) | SRC | |
| Water SCHEMBL7411075 | 0.75 | SRC (0.54) | SRCPRKACAPRKACGPRKACB | |
| Water SCHEMBL7404843 | 0.74 | GPR35 (0.42) | SRCGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631283-A | RENAL VASODILATORS, CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
| US-4490374-A | CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0107398-A1 | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-05-02 | — | — | EP | disclosed |