Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 13/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3403683 | 0.87 | TXNRD1 (0.57) | TXNRD1GSRLMNAMAPTS1PR4 | |
| SCHEMBL9042043 | 0.87 | TXNRD1 (0.57) | TXNRD1GSRLMNAMAPTS1PR4 | |
| SCHEMBL10654754 | 0.85 | TXNRD1 (0.55) | TXNRD1GSRMAPTS1PR4S1PR1 | |
| SCHEMBL2855541 | 0.85 | KCNH2 (0.47) | TXNRD1GSRLMNAALDH1A1MAPT | |
| SCHEMBL3404683 | 0.85 | TXNRD1 (0.42) | TXNRD1GSRLMNAMAPTS1PR4 | |
| SCHEMBL740933 | 0.84 | MAPT (0.56) | TXNRD1GSRLMNAALDH1A1MAPT | |
| SCHEMBL9794246 | 0.84 | TXNRD1 (0.53) | TXNRD1GSRLMNAALDH1A1MAPT | |
| SCHEMBL9794390 | 0.84 | TXNRD1 (0.50) | TXNRD1GSRMAPTS1PR4S1PR1 | |
| Hydrochloric Acid SCHEMBL10829567 | 0.84 | CHRM2 (0.46) | TXNRD1GSRLMNAALDH1A1MAPT | |
| SCHEMBL28489675 | 0.82 | TXNRD1 (0.57) | TXNRD1GSRMAPTS1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |