Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 11/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10829567 | 0.99 | CHRM2 (0.46) | KCNH2CHRM2CHRM1DRD2ADRA2B | |
| SCHEMBL2860282 | 0.92 | NPSR1 (0.49) | TXNRD1MAPTALDH1A1GSRNPSR1 | |
| SCHEMBL3403683 | 0.87 | TXNRD1 (0.57) | TXNRD1MAPTGSRLMNANPSR1 | |
| SCHEMBL741498 | 0.85 | TXNRD1 (0.48) | TXNRD1MAPTALDH1A1GSRLMNA | |
| SCHEMBL9042043 | 0.85 | TXNRD1 (0.57) | TXNRD1MAPTGSRLMNANPSR1 | |
| SCHEMBL9794246 | 0.84 | TXNRD1 (0.53) | TXNRD1SMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL10654754 | 0.83 | TXNRD1 (0.55) | TXNRD1MAPTGSRNPSR1 | |
| SCHEMBL11358231 | 0.82 | TXNRD1 (0.49) | MAOATXNRD1MAPTGSRNPSR1 | |
| SCHEMBL9794390 | 0.82 | TXNRD1 (0.50) | TXNRD1MAPTGSRNPSR1 | |
| SCHEMBL28489675 | 0.80 | TXNRD1 (0.57) | TXNRD1MAPTGSRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551806-B1 | 6-ALKOXY-2,3-DIAMINOPYRIDINE COUPLERS AND USE OF SAID COUPLERS FOR THE DYEING OF KERATINOUS FIBRES | OREAL (FR) | 2010-01-20 | — | — | EP | disclosed |
| US-7044987-B2 | 6-alkoxy-2,3-diaminopyridine couplers in which the amino radical in position 2 is a monosubstituted amino radical, and use of these couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2006-05-16 | — | — | US | disclosed |
| EP-1551806-A1 | 6-ALKOXY-2,3-DIAMINOPYRIDINE COUPLERS AND USE OF SAID COUPLERS FOR THE DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2005-07-13 | — | — | EP | disclosed |
| US-20050060814-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers in which the amino radical in position 2 is a monosubstituted amino radical, and use of these couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-03-24 | — | — | US | disclosed |
| WO-2004031152-A1 | 6-ALKOXY-2,3-DIAMINOPYRIDINE COUPLERS AND USE OF SAID COUPLERS FOR THE DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050060814-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers in which the amino radical in position 2 is a monosubstituted amino radical, and use of these couplers for dyeing keratin fibres | KRT18, QDPR, PYCR1 | KCNH2 217/4885CHRM2 1733/4885CHRM1 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.