Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 5/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7418516 | 0.96 | ITGB3 (0.49) | ITGB3ITGA2BF2KCNA5MMP3 | |
| SCHEMBL7695516 | 0.95 | ITGB3 (0.53) | ITGB3ITGA2BF2KCNA5MMP3 | |
| SCHEMBL7420817 | 0.95 | ITGB3 (0.56) | ITGB3ITGA2BKCNA5MMP3MMP13 | |
| SCHEMBL7415039 | 0.94 | ITGB3 (0.52) | ITGB3ITGA2BF2KCNA5MMP3 | |
| SCHEMBL7415221 | 0.92 | ITGB3 (0.53) | ITGB3ITGA2BKCNA5MMP3MMP13 | |
| Trifluoroacetic Acid SCHEMBL7412846 | 0.91 | ITGB3 (0.49) | ITGB3ITGA2BF2KCNA5MMP3 | |
| Trifluoroacetic Acid SCHEMBL7415231 | 0.91 | ITGB3 (0.52) | ITGB3ITGA2BF2KCNA5MMP3 | |
| Trifluoroacetic Acid SCHEMBL7413576 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BF2KCNA5MMP3 | |
| SCHEMBL7411712 | 0.90 | TDP1 (0.59) | ITGB3ITGA2BKCNA5MMP3MMP13 | |
| SCHEMBL7420563 | 0.90 | MMP2 (0.61) | ITGB3ITGA2BKCNA5MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344484-B1 | TREATMENT OF TUMOR GROWTH, METASTASIS, OSTEOPOROSIS, RESTENOSIS, INFLAMMATION, MACULAR DEGENERATION, DIABETIC RETINOPATHY, AND RHEUMATOID ARTHRITIS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-02-05 | — | — | US | claimed |
| EP-1159262-A1 | TYROSINE ALKOXYGUANIDINES AS INTEGRIN INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | claimed |
| WO-2000047552-A1 | TYROSINE ALKOXYGUANIDINES AS INTEGRIN INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2000-08-17 | — | — | WO | claimed |