Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569230 | 0.84 | CTSS (1.00) | CTSS | |
| SCHEMBL7483405 | 0.84 | CTSS (1.00) | CTSS | |
| SCHEMBL6795452 | 0.78 | CTSS (0.81) | CTSS | |
| SCHEMBL7032794 | 0.78 | CTSS (1.00) | CTSS | |
| SCHEMBL7393092 | 0.77 | CTSS (1.00) | CTSS | |
| SCHEMBL7062841 | 0.75 | CTSS (1.00) | CTSS | |
| SCHEMBL7389651 | 0.75 | CTSS (0.79) | CTSS | |
| SCHEMBL7566545 | 0.74 | CTSS (0.91) | CTSS | |
| SCHEMBL7397903 | 0.74 | CTSS (0.84) | CTSS | |
| SCHEMBL7240074 | 0.73 | CTSS (1.00) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155011-A1 | DI- AND TRIPEPTIDE NITRILE DERIVATIVES AS INHIBITORS OF CATHEPSIN L AND CATHEPSIN S | AstraZeneca AB (SE) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000049008-A1 | DI- AND TRIPEPTIDE NITRILE DERIVATIVES AS INHIBITORS OF CATHEPSIN L AND CATHEPSIN S | ASTRAZENECA AB (SE) | 2000-08-24 | — | — | WO | disclosed |