Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483405 | 1.00 | CTSS (1.00) | CTSS | |
| SCHEMBL7567190 | 0.86 | CTSS (0.76) | CTSS | |
| SCHEMBL7415085 | 0.84 | CTSS (0.72) | CTSS | |
| SCHEMBL7393092 | 0.84 | CTSS (1.00) | CTSS | |
| SCHEMBL7062841 | 0.82 | CTSS (1.00) | CTSS | |
| SCHEMBL7566545 | 0.81 | CTSS (0.91) | CTSS | |
| SCHEMBL6795452 | 0.81 | CTSS (0.81) | CTSS | |
| SCHEMBL7032794 | 0.81 | CTSS (1.00) | CTSS | |
| SCHEMBL6801126 | 0.79 | CTSS (0.86) | CTSS | |
| SCHEMBL7240074 | 0.79 | CTSS (1.00) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002538151-A | — | — | 2002-11-12 | — | — | JP | claimed |
| EP-1159273-A1 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CATHEPSIN S | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2001-12-05 | — | — | EP | claimed |
| WO-2000051998-A1 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CATHEPSIN S | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-09-08 | — | — | WO | claimed |