Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.73 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.73 |
| ▸ | FPR2 | P25090 | 13/20 | 0.39 |
| ▸ | FPR1 | P21462 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7417478 | 0.97 | ITGB3 (0.69) | ITGB3ITGA2BFPR2FPR1POLB | |
| Trifluoroacetic Acid SCHEMBL7411886 | 0.94 | ITGB3 (0.65) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7449818 | 0.91 | ITGB3 (0.70) | ITGB3ITGA2BFPR2FPR1POLB | |
| Hydrochloric Acid SCHEMBL7447965 | 0.90 | ITGB3 (0.69) | ITGB3ITGA2BFPR2FPR1POLB | |
| SCHEMBL7448710 | 0.88 | ITGB3 (0.71) | ITGB3ITGA2BFPR2FPR1POLB | |
| SCHEMBL7413115 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7446837 | 0.87 | ITGB3 (0.67) | ITGB3ITGA2BFPR2FPR1POLB | |
| SCHEMBL7455162 | 0.87 | ITGB3 (0.67) | ITGB3ITGA2BFPR2FPR1POLB | |
| Acetic Acid SCHEMBL7418347 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7449994 | 0.85 | ITGB3 (0.62) | ITGB3ITGA2BFPR2FPR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |
| JP-3034046-B2 | — | — | 2000-04-17 | — | — | JP | claimed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | claimed |
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | disclosed |