Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.55 |
| ▸ | FPR2 | P25090 | 13/20 | 0.43 |
| ▸ | FPR1 | P21462 | 9/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7418347 | 0.97 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1CA12 | |
| Trifluoroacetic Acid SCHEMBL7411809 | 0.94 | ITGB3 (0.50) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7446276 | 0.90 | ITGB3 (0.52) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7415142 | 0.88 | ITGB3 (0.73) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| Acetic Acid SCHEMBL7417478 | 0.87 | ITGB3 (0.69) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7455089 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BFPR2FPR1 | |
| Trifluoroacetic Acid SCHEMBL7411886 | 0.84 | ITGB3 (0.65) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7450172 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL8122590 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BFPR2FPR1CA12 | |
| SCHEMBL7419658 | 0.82 | ITGB3 (0.36) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |
| JP-3034046-B2 | — | — | 2000-04-17 | — | — | JP | claimed |
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | claimed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | claimed |
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | disclosed |