SCHEMBL741523

SCHEMBL741523

Clc1ccccc1-c1cocn1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.44
SCN9A Q15858 2/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
NOTUM Q6P988 2/20 0.43
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
CYP19A1 P11511 1/20 0.40
CYP2A6 P11509 1/20 0.40
GRM5 P41594 1/20 0.39
LDHA P00338 1/20 0.39
MAOB P27338 1/20 0.39
ATM Q13315 1/20 0.39
ATP4A P20648 2/20 0.38
ATP4B P51164 2/20 0.38
CNR2 P34972 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28474696 0.78 SCN9A (0.43) SCN9ANPC1RAB9ASMN1; SMN2TP53
SCHEMBL7771560 0.77 SCN9A (0.45) SCN9ANPC1SMN1; SMN2TP53HPGD
SCHEMBL26259970 0.77 SCN9A (0.47) SCN9ANPC1SMN1; SMN2TP53HPGD
SCHEMBL26259957 0.77 SCN9A (0.44) SCN9A
SCHEMBL5650569 0.76 SCN9A (0.44) IDO1SCN9ANPC1RAB9ASMN1; SMN2
SCHEMBL18543166 0.76 SCN9A (0.44) IDO1SCN9ANPC1RAB9ASMN1; SMN2
SCHEMBL21054847 0.76 ALDH1A1 (0.46) IDO1SCN9ANPC1RAB9ASMN1; SMN2
SCHEMBL30607676 0.76 SCN9A (0.44) IDO1SCN9ANPC1RAB9ASMN1; SMN2
SCHEMBL16151990 0.76 SCN9A (0.44) IDO1SCN9ANPC1RAB9ASMN1; SMN2
SCHEMBL6205082 0.76 SCN9A (0.47) IDO1SCN9ANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9201302-B2 Negative-working lithographic printing plate precursor EASTMAN KODAK COMPANY (US) 2015-12-01 US disclosed
US-20150099229-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR BANK OF AMERICA, N.A., AS AGENT 2015-04-09 US disclosed
US-8137896-B2 Method of preparing lithographic printing plates EASTMAN KODAK COMPANY (US) 2012-03-20 US disclosed