Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30607676 | 1.00 | SCN9A (0.44) | SCN9AIDO1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL26259970 | 0.77 | SCN9A (0.47) | SCN9AHSD17B10ALDH1A1MAPK1HDAC4 | |
| SCHEMBL26259957 | 0.77 | SCN9A (0.44) | SCN9AHDAC4CASP6EDNRBEDNRA | |
| SCHEMBL5650569 | 0.76 | SCN9A (0.44) | SCN9AIDO1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL741523 | 0.76 | IDO1 (0.44) | SCN9AIDO1LMNAALDH1A1MAOB | |
| SCHEMBL6205082 | 0.76 | SCN9A (0.47) | SCN9AIDO1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL21054847 | 0.76 | ALDH1A1 (0.46) | SCN9AIDO1HSD17B10ALDH1A1HDAC4 | |
| SCHEMBL16151990 | 0.76 | SCN9A (0.44) | SCN9AIDO1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL19138133 | 0.74 | IMPDH2 (0.34) | SCN9ALMNAHSD17B10ALDH1A1MAPT | |
| SCHEMBL19584693 | 0.74 | F2RL1 (0.48) | SCN9ARAB9ANPC1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025847-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2022-02-08 | — | — | CN | disclosed |
| EP-2855419-B1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARB OXYLIC ACIDS | BOEHRINGER INGELHEIM INT (DE) | 2017-03-01 | — | — | EP | disclosed |