Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.55 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.55 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.55 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | SELP | P16109 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095615 | 0.98 | PPARA (0.59) | PPARAPPARGPOLBPLAAT3PLAAT5 | |
| SCHEMBL503571 | 0.94 | PLAAT3 (0.61) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL5192275 | 0.89 | KDM4E (0.57) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL4086224 | 0.88 | ALOX5 (0.70) | ALOX5 | |
| SCHEMBL7156624 | 0.88 | PLAAT3 (0.56) | PPARAPPARGPOLBPLAAT3PLAAT5 | |
| SCHEMBL6943609 | 0.88 | PPARA (0.56) | PPARAPPARGPOLBALOX5SELP | |
| SCHEMBL10599216 | 0.88 | PPARA (0.50) | PPARAPPARGPOLBPLAAT3PLAAT5 | |
| SCHEMBL9175204 | 0.87 | PPARA (0.58) | PPARAPPARGPOLBPLAAT3PLAAT5 | |
| SCHEMBL2221405 | 0.87 | KDM4E (0.59) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL347209 | 0.87 | FFAR4 (0.61) | ALOX5LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| US-6150412-A | SUCH AS 4-(5-HYDROXY-4-METHOXY-2-NITROPHENYL)BUTANOIC ACID; ADMINISTERING TO INHIBIT CATECHOL-O-METHYL TRANSFERASE; TREATING PARKINSON'S DISEASE OR HYPERTENSION | ORION-YHTYMA OY (FI) | 2000-11-21 | — | — | US | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| WO-1996037456-A1 | NEW CATECHOL DERIVATIVES | Orion-Yhtymä Oy (FI) | 1996-11-28 | — | — | WO | disclosed |