Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414100 | 0.87 | GAA (0.33) | HTTGAA | |
| SCHEMBL7412572 | 0.83 | HTT (0.35) | HTTSMN1; SMN2POLBTSHRGAA | |
| SCHEMBL7411412 | 0.81 | HTT (0.34) | HTTSMN1; SMN2POLBTSHRGAA | |
| SCHEMBL7415393 | 0.80 | CHRM2 (0.34) | HTTSMN1; SMN2POLBTSHR | |
| SCHEMBL7410791 | 0.71 | KDM4E (0.36) | HTTSMN1; SMN2GAA | |
| SCHEMBL7406591 | 0.70 | HSD17B10 (0.38) | SMN1; SMN2TSHR | |
| SCHEMBL13315461 | 0.70 | SMN1; SMN2 (0.44) | HTTSMN1; SMN2POLBTSHR | |
| SCHEMBL7413113 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL7409129 | 0.69 | HTR4 (0.40) | GAA | |
| SCHEMBL7417661 | 0.68 | HTR4 (0.39) | HTTSMN1; SMN2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |