Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.31 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415355 | 0.87 | HTT (0.32) | GAAHTT | |
| SCHEMBL7410791 | 0.85 | KDM4E (0.36) | GAAKDM4EALDH1A1HTR4NPC1 | |
| SCHEMBL7409129 | 0.83 | HTR4 (0.40) | GAAKDM4EALDH1A1NQO2HTR4 | |
| SCHEMBL7417661 | 0.82 | HTR4 (0.39) | GAAKDM4EALDH1A1HTR4NPC1 | |
| SCHEMBL7417517 | 0.76 | HTR4 (0.42) | GAAKDM4EALDH1A1NQO2HTR4 | |
| SCHEMBL13315460 | 0.74 | ALDH1A1 (0.41) | GAAKDM4EALDH1A1NQO2HTR4 | |
| SCHEMBL7410744 | 0.74 | SERPINH1 (0.39) | KDM4EALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL7419404 | 0.74 | KDM4E (0.40) | GAAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL7410564 | 0.72 | KDM4E (0.43) | GAAKDM4EALDH1A1HTR4NPC1 | |
| SCHEMBL7415393 | 0.70 | CHRM2 (0.34) | HTR4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |