Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378715 | 0.88 | TSHR (0.60) | L3MBTL1GAARARBTSHRTP53 | |
| SCHEMBL6642095 | 0.87 | L3MBTL1 (0.50) | L3MBTL1GAAMAPK1RARBMAPT | |
| SCHEMBL19130182 | 0.85 | TP53 (0.66) | L3MBTL1RARBTSHRTP53PLA2G4B | |
| SCHEMBL11680771 | 0.84 | L3MBTL1 (0.60) | L3MBTL1MAPK1MAPTTSHRTP53 | |
| SCHEMBL99263 | 0.84 | GAA (0.57) | L3MBTL1GAAMAPK1RARBMAPT | |
| SCHEMBL19130183 | 0.83 | TP53 (0.69) | GAARARBTSHRTP53PLA2G4B | |
| SCHEMBL7909288 | 0.83 | RARB (0.63) | L3MBTL1RARBTSHRTP53PLA2G4B | |
| SCHEMBL13385664 | 0.83 | TP53 (0.69) | GAARARBTSHRTP53PLA2G4B | |
| SCHEMBL19130711 | 0.83 | TP53 (0.69) | GAARARBTSHRTP53PLA2G4B | |
| Water SCHEMBL20916139 | 0.83 | GAA (0.56) | L3MBTL1GAAMAPK1RARBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |