Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817346 | 0.89 | SLC1A1 (0.43) | KMT2ATSHRCYP2C19MEN1TACR1 | |
| SCHEMBL28192047 | 0.81 | KMT2A (0.56) | KMT2ATSHRLTA4HCYP2C19CYP3A4 | |
| SCHEMBL10509257 | 0.79 | LTA4H (0.45) | KMT2ATSHRLTA4HCYP2C19CYP3A4 | |
| SCHEMBL10740109 | 0.79 | LTA4H (0.45) | KMT2ATSHRLTA4HCYP2C19CYP3A4 | |
| SCHEMBL10511795 | 0.79 | LTA4H (0.45) | KMT2ATSHRLTA4HCYP2C19CYP3A4 | |
| SCHEMBL10511562 | 0.79 | LTA4H (0.45) | KMT2ATSHRLTA4HCYP2C19CYP3A4 | |
| SCHEMBL9801009 | 0.76 | LTA4H (0.45) | KMT2ATSHRLTA4HCYP2C19MEN1 | |
| SCHEMBL7819088 | 0.74 | KMT2A (0.41) | KMT2ATSHRLTA4HCYP2C19MEN1 | |
| SCHEMBL14625499 | 0.74 | KMT2A (0.58) | KMT2ATSHRCYP2C19CYP3A4MEN1 | |
| SCHEMBL7045988 | 0.73 | LTA4H (0.45) | KMT2ALTA4HCYP2C19MEN1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |