Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.45 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415667 | 1.00 | MME (0.45) | MMEGPR34PTGDRPOLBGAA | |
| SCHEMBL7419793 | 0.95 | MME (0.48) | MMEGPR34PTGDRPOLBGAA | |
| SCHEMBL7419799 | 0.95 | MME (0.48) | MMEGPR34PTGDRPOLBGAA | |
| SCHEMBL7341732 | 0.87 | MMEL1 (0.48) | MME | |
| SCHEMBL7413785 | 0.86 | PTPN5 (0.46) | MMEGPR34ACEACE2KIFC1 | |
| SCHEMBL7413773 | 0.86 | PTPN5 (0.46) | MMEGPR34ACEACE2KIFC1 | |
| SCHEMBL7407179 | 0.85 | MME (0.50) | MMEACEACE2ACP3CPA1 | |
| SCHEMBL7407171 | 0.85 | MME (0.50) | MMEACEACE2ACP3CPA1 | |
| SCHEMBL7412188 | 0.81 | MME (0.47) | MMEGPR34ACEACE2CPA1 | |
| SCHEMBL7412178 | 0.81 | MME (0.47) | MMEGPR34ACEACE2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |