Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418266 | 0.93 | NAMPT (0.53) | NAMPTMMP9MMP13MMP1ALDH1A1 | |
| SCHEMBL7410709 | 0.92 | MMP9 (0.52) | NAMPTMMP9MMP13MMP1ALDH1A1 | |
| SCHEMBL7322218 | 0.80 | NAMPT (0.55) | NAMPTMMP9MMP13MMP1ALDH1A1 | |
| SCHEMBL7316583 | 0.78 | NAMPT (0.53) | NAMPTMMP9MMP13MMP1ALDH1A1 | |
| SCHEMBL7325342 | 0.77 | NAMPT (0.56) | NAMPTMMP9MMP13MMP1ALDH1A1 | |
| SCHEMBL7316683 | 0.77 | NAMPT (0.52) | NAMPTMMP9MMP13MMP1ALDH1A1 | |
| SCHEMBL7410712 | 0.76 | MMP9 (0.50) | NAMPTMMP9MMP13MMP1ALDH1A1 | |
| SCHEMBL7318343 | 0.75 | NAMPT (0.49) | NAMPTMMP9MMP13MMP1ALDH1A1 | |
| SCHEMBL7314523 | 0.74 | NAMPT (0.55) | NAMPTMMP9MMP13MMP1ALDH1A1 | |
| SCHEMBL7319361 | 0.74 | MMP9 (0.56) | NAMPTMMP9MMP13MMP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962481-A | ANTIARTHRITIC AGENTS; ANTITUMOR AGENTS; WOUND HEALING AGENTS;ANTIULCER AGENTS; ORAL DISEASES; CENTRAL NERVOUS SYTEM DISORDERS; ANTIINFLAMMATORY AGENTS; CONGESTIVE HEART FAILURE;VISION DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1999-10-05 | — | — | US | disclosed |