Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP7 | P09237 | 5/20 | 0.66 |
| ▸ | MMP9 | P14780 | 3/20 | 0.66 |
| ▸ | MMP10 | P09238 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | BMP1 | P13497 | 8/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414877 | 1.00 | MMP7 (0.66) | MMP7MMP9MMP10ALDH1A1MAPT | |
| SCHEMBL7419489 | 0.92 | MMP7 (0.77) | MMP7MMP9MMP10ALDH1A1MAPT | |
| SCHEMBL7417246 | 0.92 | MMP7 (0.65) | MMP7MMP9MMP10ALDH1A1MEP1B | |
| SCHEMBL7419926 | 0.87 | MMP7 (0.60) | MMP7MMP9MMP10ALDH1A1MAPT | |
| SCHEMBL7414393 | 0.87 | MMP7 (0.70) | MMP7MMP9MMP10ALDH1A1MAPT | |
| SCHEMBL7417827 | 0.86 | MMP7 (0.59) | MMP7MMP9MMP10MEP1BBMP1 | |
| SCHEMBL7411340 | 0.86 | MMP7 (0.59) | MMP7MMP9MMP10MEP1BBMP1 | |
| SCHEMBL7417364 | 0.86 | MMP7 (0.69) | MMP7MMP9MMP10ALDH1A1MAPT | |
| SCHEMBL7417547 | 0.86 | MMP7 (0.69) | MMP7MMP9MMP10ALDH1A1MAPT | |
| SCHEMBL7423461 | 0.83 | MMP7 (0.58) | MMP7MMP9MMP10ALDH1A1MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |
| EP-1009737-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999006340-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |