Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP7 | P09237 | 3/20 | 0.58 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP10 | P09238 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | BMP1 | P13497 | 6/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416682 | 0.96 | MMP7 (0.58) | MMP7MMP9MMP10ALDH1A1GABRG2 | |
| SCHEMBL7419926 | 0.88 | MMP7 (0.60) | MMP7MMP9MMP10ALDH1A1BMP1 | |
| SCHEMBL7417246 | 0.88 | MMP7 (0.65) | MMP7MMP9MMP10ALDH1A1BMP1 | |
| SCHEMBL7414547 | 0.87 | MMP7 (0.54) | MMP7MMP9MMP10FFAR4BMP1 | |
| SCHEMBL7412866 | 0.86 | MMP7 (0.61) | MMP7MMP9MMP10ALDH1A1MMP13 | |
| SCHEMBL7418672 | 0.85 | MMP9 (0.57) | MMP7MMP9MMP10ALDH1A1MMP13 | |
| SCHEMBL7413136 | 0.85 | MMP9 (0.53) | MMP7MMP9MMP10MMP13CA1 | |
| SCHEMBL7411120 | 0.83 | MMP7 (0.54) | MMP7MMP9MMP10FFAR4BMP1 | |
| SCHEMBL7415839 | 0.83 | MMP7 (0.66) | MMP7MMP9MMP10ALDH1A1BMP1 | |
| SCHEMBL7414877 | 0.83 | MMP7 (0.66) | MMP7MMP9MMP10ALDH1A1BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |
| EP-1009737-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999006340-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |