Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 15/20 | 0.63 |
| ▸ | AGTR2 | P50052 | 12/20 | 0.63 |
| ▸ | EDNRA | P25101 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pratosartan SCHEMBL93595 | 0.91 | AGTR1 (0.73) | AGTR1AGTR2EDNRA | |
| SCHEMBL683741 | 0.90 | AGTR1 (0.72) | AGTR1AGTR2EDNRA | |
| SCHEMBL683401 | 0.85 | AGTR1 (0.74) | AGTR1AGTR2EDNRA | |
| SCHEMBL683452 | 0.85 | AGTR1 (0.73) | AGTR1AGTR2EDNRA | |
| SCHEMBL9843867 | 0.83 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9638103 | 0.81 | PPARG (0.53) | AGTR1AGTR2 | |
| SCHEMBL9076746 | 0.79 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL9847832 | 0.78 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL6536063 | 0.78 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8072083 | 0.78 | GP6 (0.56) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000037075-A1 | COMBINATION OF AN AT1 ANGIOTENSIN II RECEPTOR ANTAGONIST AND AN IMMUNOSUPPRESSANT | SANOFI-SYNTHELABO (FR) | 2000-06-29 | — | — | WO | disclosed |