Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.60 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851416 | 0.95 | AGTR1 (0.61) | AGTR1AGTR2LMNAENPP2 | |
| SCHEMBL8972057 | 0.90 | AGTR1 (0.71) | AGTR1AGTR2LMNAPDE4APDE4B | |
| SCHEMBL8972687 | 0.90 | AGTR1 (0.61) | AGTR1AGTR2LMNAENPP2TP53 | |
| SCHEMBL9638103 | 0.87 | PPARG (0.53) | AGTR1AGTR2LMNA | |
| SCHEMBL9425035 | 0.87 | AGTR1 (0.55) | AGTR1AGTR2LMNAPDE4APDE4B | |
| SCHEMBL8972204 | 0.86 | AGTR1 (0.59) | AGTR1AGTR2LMNAENPP2TP53 | |
| SCHEMBL9847782 | 0.86 | AGTR2 (0.61) | AGTR1AGTR2 | |
| SCHEMBL29486817 | 0.85 | AGTR1 (0.72) | AGTR1AGTR2ENPP2 | |
| SCHEMBL7622112 | 0.85 | AGTR1 (0.72) | AGTR1AGTR2ENPP2 | |
| SCHEMBL8972529 | 0.84 | AGTR1 (0.62) | AGTR1AGTR2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | claimed |