Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 9/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418286 | 0.80 | TAAR1 (0.60) | SCN4ATAAR1HTR2ASLC6A2SLC6A4 | |
| SCHEMBL6997156 | 0.79 | TAAR1 (0.44) | SCN4ATAAR1HTR2ASLC6A4 | |
| SCHEMBL7416098 | 0.77 | AOC3 (0.38) | SCN4ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7424290 | 0.77 | HTR2A (0.50) | IDO1TDO2TAAR1HTR2ACHRNA7 | |
| SCHEMBL7414044 | 0.77 | HTR2A (0.45) | SCN4ATAAR1HTR2ACHRNA7SLC6A2 | |
| SCHEMBL4740736 | 0.76 | HTR2A (0.67) | IDO1TDO2TAAR1HTR2ACHRNA7 | |
| SCHEMBL3905408 | 0.72 | TAAR1 (0.41) | SCN4AIDO1TDO2TAAR1HTR2A | |
| SCHEMBL7416552 | 0.70 | NOS2 (0.43) | IDO1TDO2TAAR1HTR2AOPRM1 | |
| SCHEMBL4371628 | 0.70 | TAAR1 (0.56) | IDO1TDO2TAAR1HTR2ACHRNA7 | |
| SCHEMBL3911314 | 0.69 | HTR2A (0.45) | TAAR1HTR2ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988003147-A1 | SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | disclosed |