Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 2/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371628 | 0.94 | TAAR1 (0.56) | HTR2ATAAR1IDO1TDO2PNMT | |
| SCHEMBL3415393 | 0.90 | HTR2A (0.64) | HTR2ATAAR1IDO1TDO2PNMT | |
| Hydrochloric Acid SCHEMBL10707847 | 0.89 | HTR2A (0.61) | HTR2ATAAR1IDO1TDO2PNMT | |
| SCHEMBL4740736 | 0.88 | HTR2A (0.67) | HTR2ATAAR1IDO1TDO2CHRNB2 | |
| SCHEMBL3911314 | 0.84 | HTR2A (0.45) | HTR2ATAAR1PNMTCHRNB2CHRNA4 | |
| SCHEMBL3398977 | 0.82 | HTR2A (0.48) | HTR2ATAAR1PNMTCHRNB2CHRNA4 | |
| SCHEMBL7416552 | 0.81 | NOS2 (0.43) | HTR2ATAAR1IDO1TDO2PNMT | |
| SCHEMBL1581317 | 0.79 | PNMT (0.45) | HTR2ATAAR1PNMTCHRNB2CHRNA4 | |
| SCHEMBL5947869 | 0.78 | HRH1 (0.59) | HTR2ATAAR1IDO1TDO2PNMT | |
| SCHEMBL11080398 | 0.78 | PNMT (0.48) | TAAR1IDO1TDO2PNMTACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988003147-A1 | SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | disclosed |