Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410337 | 0.90 | ACHE (0.55) | ACHESLC6A2SLC6A4SLC6A3MCHR1 | |
| SCHEMBL7409350 | 0.89 | SLC6A2 (0.57) | ACHESLC6A2SLC6A4SLC6A3MCHR1 | |
| SCHEMBL7414785 | 0.85 | SLC6A2 (0.58) | ACHESLC6A2SLC6A4SLC6A3MCHR1 | |
| SCHEMBL7407220 | 0.85 | MCHR1 (0.54) | DRD4ACHEMCHR1BACE1KMT2A | |
| SCHEMBL7412318 | 0.81 | SLC6A2 (0.53) | DRD4ACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7415717 | 0.80 | SLC6A2 (0.54) | DRD4ACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7413825 | 0.79 | SLC6A2 (0.53) | ACHESLC6A2SLC6A4SLC6A3MCHR1 | |
| SCHEMBL7417953 | 0.79 | MCHR1 (0.52) | ACHESLC6A2SLC6A4SLC6A3MCHR1 | |
| Hydrochloric Acid SCHEMBL7419435 | 0.78 | SLC6A2 (0.52) | ACHESLC6A2SLC6A4SLC6A3MCHR1 | |
| SCHEMBL7458788 | 0.78 | SLC6A4 (0.52) | ACHESLC6A2SLC6A4SLC6A3MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |