Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | S100A4 | P26447 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24186657 | 0.78 | ALDH1A1 (0.47) | ALDH1A1GAATDP1MEN1KMT2A | |
| SCHEMBL187697 | 0.76 | ALDH1A1 (0.61) | ALDH1A1GAATYMSTDP1MEN1 | |
| SCHEMBL29626558 | 0.76 | ALDH1A1 (0.61) | ALDH1A1GAATYMSTDP1MEN1 | |
| SCHEMBL7472269 | 0.75 | GAA (0.67) | ALDH1A1GAATDP1MEN1KMT2A | |
| SCHEMBL9056779 | 0.72 | ALDH1A1 (0.52) | ALDH1A1GAATYMSTDP1MEN1 | |
| SCHEMBL19586839 | 0.70 | CRBN (0.54) | ALDH1A1TDP1TSHRCYP1A2 | |
| Pyrene SCHEMBL27684019 | 0.69 | ALDH1A1 (0.63) | ALDH1A1GAATYMSTDP1MEN1 | |
| SCHEMBL17283584 | 0.68 | ALDH1A1 (0.52) | ALDH1A1GAATYMSTDP1MEN1 | |
| SCHEMBL9055141 | 0.68 | ALDH1A1 (0.52) | ALDH1A1GAATYMSTDP1MEN1 | |
| SCHEMBL5068468 | 0.68 | ALDH1A1 (0.52) | ALDH1A1GAATYMSTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877185-A | THERAPY FOR CANCER OR RETROVIRUS | OCTAMER, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| WO-1996022791-A9 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | — | 1996-10-03 | — | — | WO | disclosed |
| WO-1996022791-A1 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | OCTAMER, INC. (US) | 1996-08-01 | — | — | WO | disclosed |