Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.46 |
| ▸ | PDE4A | P27815 | 5/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460382 | 0.83 | PDE4A (0.44) | SLC6A4PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7866876 | 0.81 | SLC6A4 (0.47) | SLC6A4PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL26921463 | 0.80 | SLC6A4 (0.58) | SLC6A4PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7419178 | 0.76 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6546375 | 0.75 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7415768 | 0.75 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7425652 | 0.69 | PDE4A (0.69) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5306792 | 0.66 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL31062122 | 0.66 | CASP1 (0.54) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11817961 | 0.66 | PDE4A (0.75) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636025-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-07-18 | — | — | EP | claimed |
| EP-0636025-A4 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES. | — | 1995-02-22 | — | — | EP | claimed |
| EP-0636025-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-01 | — | — | EP | claimed |
| WO-1993019750-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-14 | — | — | WO | claimed |
| EP-0636025-A4 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES. | — | 1995-02-22 | — | — | EP | disclosed |
| EP-0636025-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993019750-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |