SCHEMBL7416636

SCHEMBL7416636

CC(C)c1cccc2c1C(=O)N(CSc1nnnn1C)S2(=O)=O

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7416331 0.86 ELANE (1.00) ELANE
SCHEMBL7411771 0.83 ELANE (0.67) ELANE
SCHEMBL7421272 0.82 ELANE (0.63) ELANE
SCHEMBL8801878 0.82 ELANE (0.81) ELANE
SCHEMBL7415642 0.80 ELANE (1.00) ELANE
SCHEMBL7018079 0.78 ELANE (0.66) ELANE
SCHEMBL7465823 0.77 ELANE (0.59) ELANE
SCHEMBL7420954 0.77 ELANE (1.00) ELANE
SCHEMBL7420501 0.76 ELANE (1.00) ELANE
SCHEMBL8521554 0.75 ELANE (0.60) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0471756-B1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF SANOFI SA (FR) 1997-10-29 EP claimed
EP-0471756-A4 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF 1992-04-08 EP claimed
EP-0471756-A1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF. STERLING WINTHROP INC (US) 1992-02-26 EP claimed
WO-1990013549-A1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF STERLING WINTHROP INC. (US) 1990-11-15 WO claimed