SCHEMBL7465823

SCHEMBL7465823

Cc1nnc(SCN2C(=O)c3c(C(C)C)cccc3S2(=O)=O)s1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 19/20 0.59
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9690974 0.91 MEN1 (0.51) ELANERAB9A
SCHEMBL7018079 0.79 ELANE (0.66) ELANE
SCHEMBL7416636 0.77 ELANE (0.75) ELANE
SCHEMBL8521554 0.76 ELANE (0.60) ELANE
SCHEMBL7018684 0.74 ELANE (0.62) ELANE
SCHEMBL7416331 0.74 ELANE (1.00) ELANE
SCHEMBL7310086 0.73 ELANE (0.60) ELANE
SCHEMBL7411771 0.72 ELANE (0.67) ELANE
SCHEMBL8801878 0.71 ELANE (0.81) ELANE
SCHEMBL9407219 0.70 ELANE (0.67) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1990013549-A1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF STERLING WINTHROP INC. (US) 1990-11-15 WO claimed