Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 3/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.62 |
| ▸ | CASP1 | P29466 | 6/20 | 0.55 |
| ▸ | ITGAV | P06756 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669839 | 0.82 | ITGAV (0.66) | SLC1A3SLC1A2SLC1A1CASP1ITGAV | |
| SCHEMBL6669846 | 0.82 | ITGAV (0.66) | SLC1A3SLC1A2SLC1A1CASP1ITGAV | |
| SCHEMBL7376542 | 0.80 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1ATML3MBTL1 | |
| SCHEMBL27525484 | 0.76 | ATM (0.61) | SLC1A3SLC1A2SLC1A1CASP1ITGAV | |
| SCHEMBL27559330 | 0.76 | L3MBTL1 (0.61) | SLC1A3SLC1A2SLC1A1CASP1ITGAV | |
| SCHEMBL6250115 | 0.76 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1ATML3MBTL1 | |
| SCHEMBL14798294 | 0.75 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1CASP1ITGAV | |
| SCHEMBL27895996 | 0.75 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1CASP1ITGAV | |
| SCHEMBL10765699 | 0.75 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1CASP1ITGAV | |
| SCHEMBL5777753 | 0.75 | FABP4 (0.50) | ITGAVATML3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821241-A | INHIBIT BINDING OF FIBRINOGEN TO BLOOD PLATELETS, INHIBIT AGGREGATION OF BLOOD PLATELETS, PREVENT OR TREAT THROMBUS OR EMBOLUS FORMATION | MERCK & CO., INC. (US) | 1998-10-13 | — | — | US | disclosed |
| WO-1994018981-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-09-01 | — | — | WO | disclosed |