Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16371594 | 0.88 | HTT (0.49) | SMN1; SMN2HSD17B10KMT2AHTTMEN1 | |
| SCHEMBL7410882 | 0.82 | HTT (0.57) | SMN1; SMN2HSD17B10KMT2AHTTMEN1 | |
| SCHEMBL18737955 | 0.82 | HTT (0.46) | SMN1; SMN2HSD17B10KMT2AHTTMEN1 | |
| SCHEMBL167967 | 0.80 | POLB (0.51) | SMN1; SMN2HSD17B10KMT2AHTTMAPT | |
| SCHEMBL3298778 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTGAALMNAALDH1A1 | |
| SCHEMBL18737828 | 0.77 | ALDH1A1 (0.45) | SMN1; SMN2HSD17B10KMT2AMEN1MAPT | |
| SCHEMBL8186768 | 0.77 | LCK (0.53) | HSD17B10KMT2AMEN1MAPTGAA | |
| SCHEMBL166372 | 0.77 | POLB (0.48) | SMN1; SMN2HSD17B10KMT2AHTTMAPT | |
| SCHEMBL5734883 | 0.77 | GAA (0.47) | SMN1; SMN2HSD17B10KMT2AHTTMEN1 | |
| SCHEMBL166131 | 0.77 | KDM4E (0.39) | SMN1; SMN2HSD17B10KMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |