Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417069 | 0.91 | REN (0.50) | REN | |
| SCHEMBL7321559 | 0.88 | CTSS (0.36) | RENCTSSCTSLCTSB | |
| SCHEMBL9642432 | 0.84 | REN (0.39) | RENCTSS | |
| SCHEMBL7367978 | 0.83 | CTSS (0.37) | RENCTSSCTSLCTSB | |
| SCHEMBL7382471 | 0.79 | CTSS (0.39) | RENCTSSCTSLCTSB | |
| SCHEMBL9642437 | 0.77 | REN (0.48) | REN | |
| SCHEMBL9575024 | 0.77 | REN (0.39) | RENCTSS | |
| SCHEMBL9641500 | 0.74 | CTSS (0.31) | CTSS | |
| SCHEMBL9575107 | 0.74 | REN (0.38) | RENCTSSCTSLCTSB | |
| SCHEMBL9574993 | 0.73 | REN (0.39) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055466-A | Renin inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1991-10-08 | — | — | US | disclosed |