Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 5/20 | 0.51 |
| ▸ | CASP6 | P55212 | 3/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 13/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL8059816 | 0.90 | CASP1 (0.52) | CASP3CASP6CASP8CASP1 | |
| SCHEMBL7417068 | 0.84 | CASP1 (0.64) | CASP3CASP6CASP8CASP1HPGD | |
| Naphthalene SCHEMBL8059861 | 0.83 | CASP1 (0.46) | CASP3CASP6CASP8CASP1 | |
| Naphthalene SCHEMBL8055399 | 0.82 | CASP3 (0.45) | CASP3CASP6CASP8CASP1 | |
| Naphthalene SCHEMBL8414586 | 0.82 | CASP1 (0.52) | CASP3CASP6CASP8CASP1 | |
| SCHEMBL6160794 | 0.82 | KMT2A (0.51) | CASP3CASP6CASP8CASP1ITGB3 | |
| Naphthalene SCHEMBL7423275 | 0.82 | CASP1 (0.45) | CASP3CASP6CASP8CASP1 | |
| Naphthalene SCHEMBL8412276 | 0.81 | CASP1 (0.58) | CASP1 | |
| Naphthalene SCHEMBL7421743 | 0.81 | CASP1 (0.48) | CASP3CASP6CASP8CASP1 | |
| Naphthalene SCHEMBL8414700 | 0.80 | CASP1 (0.46) | CASP3CASP6CASP8CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932598-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | claimed |
| WO-1998016502-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | claimed |
| WO-2001019373-A2 | METHODS AND COMPOSITIONS FOR MODULATING RESPONSIVENESS TO CORTICOSTEROIDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |